diff --git a/server/configurations/local.yaml b/server/configurations/local.yaml
index 2c4bd8f3ce..4bab089b6a 100644
--- a/server/configurations/local.yaml
+++ b/server/configurations/local.yaml
@@ -113,10 +113,7 @@ s3:
     #
     # 1. Disable SSL.
     #
-    # 2. Use "path" style S3 URLs where the bucket is part of the URL path, e.g.
-    #    http://localhost:3200/b2-eu-cen. By default the bucket name is part of
-    #    the (sub)domain, e.g. http://b2-eu-cen.localhost:3200/ and cannot be
-    #    resolved when running locally.
+    # 2. Use "path" style S3 URLs (see `use_path_style_urls` below).
     #
     # 3. Directly download the file during replication instead of going via the
     #    Cloudflare worker.
@@ -125,6 +122,17 @@ s3:
     #    not support them, specifically it doesn't support GLACIER).
     #
     #are_local_buckets: true
+    # Uncomment this to use "path" style S3 URLs.
+    #
+    # By default the bucket name is part of the (sub)domain, e.g.
+    # http://b2-eu-cen.localhost:3200/. If this is true, then we use "path"
+    # style S3 URLs where the bucket is part of the URL path, e.g.
+    # http://localhost:3200/b2-eu-cen.
+    #
+    # This is useful in scenarios when sub-domain based addressing cannot be
+    # resolved, e.g. when running a local instance, or when using MinIO as a
+    # production store.
+    #use_path_style_urls: true
 
 # Key used for encrypting customer emails before storing them in DB
 #
diff --git a/server/pkg/utils/s3config/s3config.go b/server/pkg/utils/s3config/s3config.go
index fe83ce6ea3..9b273bd612 100644
--- a/server/pkg/utils/s3config/s3config.go
+++ b/server/pkg/utils/s3config/s3config.go
@@ -104,6 +104,7 @@ func (config *S3Config) initialize() {
 	config.s3Configs = make(map[string]*aws.Config)
 	config.s3Clients = make(map[string]s3.S3)
 
+	usePathStyleURLs := viper.GetBool("s3.use_path_style_urls")
 	areLocalBuckets := viper.GetBool("s3.are_local_buckets")
 	config.areLocalBuckets = areLocalBuckets
 
@@ -116,6 +117,9 @@ func (config *S3Config) initialize() {
 			Endpoint: aws.String(viper.GetString("s3." + dc + ".endpoint")),
 			Region:   aws.String(viper.GetString("s3." + dc + ".region")),
 		}
+		if usePathStyleURLs {
+			s3Config.S3ForcePathStyle = aws.Bool(true)
+		}
 		if areLocalBuckets {
 			s3Config.DisableSSL = aws.Bool(true)
 			s3Config.S3ForcePathStyle = aws.Bool(true)